Egfl7 molecular weight
WebJun 1, 2004 · Human and mouse EGFL7 encode a 29.6 kDa protein (273 amino acids) and a 29.8 kDa (275 amino acids) protein, respectively (Soncin et al., 2003). This protein was first described to be expressed in...
Egfl7 molecular weight
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WebNov 30, 2016 · Western blot analysis detected Egfl7 at an apparent molecular mass of 41 kD, suggesting posttranslational modification. Schmidt et al. (2009) noted that EGFL7 … WebFeb 9, 2015 · Generation of Jeg3 cells overexpressing epidermal growth factor-like domain 7 (EGFL7). (A) Schematic representation of lentiviral vector containing the human EGFL7 cDNA, an internal ribosome entry site (IRES) and a green fluorescent protein (GFP) reporter gene under the control of a phosphoglycerate kinase 1 (PGK) promoter.(B and C) GFP …
WebEpidermal growth factor-like domain-containing protein 7 (EGFL7), also known as vascular endothelial statin, is an endothelial cell-derived secreted factor that regulates vascular tube formation. This protein may be … WebApr 10, 2024 · EGFL7 knock-out in vivo promoted adult neurogenesis generating neurons forming additional spines which permanently integrated into the neural circuit until old age. RNA-sequencing identified the cytokine VEGF-D …
WebOct 29, 2024 · Here, we identify that EGF like domain multiple 7 ( EGFL7) is a responsive gene to epidermal growth factor receptor (EGFR) kinase inhibition during a period when tumors are decimated. Moreover,... The Egfl7 protein (29 kDa) is composed of several putative domains: a putative cleavable signal peptide at the N-terminal end, an EMI domain, found on extracellular matrix proteins, two EGF-like domains and a leucine and valine rich C-terminal region. The first EGF-like domain has a region similar to the DSL (Delta/Serrate/Lag-2) domain found in ligands of the Notch receptors family, the second EGF-like domain is predicted to bind Ca . The Eglf7 protein is secreted and associates …
WebFeb 9, 2012 · The mouse and human Egfl7 genes are located on chromosome 2 and 9, respectively. 12, 14 The mouse gene spans 11.5 kb and consists of 11 exons, 12, 14 with a miRNA, miR126, located between exons 7 and 8 9-11 ( Figure 1 A).
WebApr 11, 2013 · EGFL7 is involved in physiological and pathological angiogenesis. Abstract Angiogenesis, defined as blood vessel formation from a preexisting vasculature, is governed by multiple signal cascades including integrin receptors, in particular integrin α V β 3. rich butterscotch barsWebThe encoded protein has 273 amino acids with the molecular weight of 29 kDa. The structure of EGFL7 contains a putative cleavable signal peptide at N-terminal, an EMI domain, two EGF-like domains and a leucine and valine rich C-terminal region. red oak longview txWebFeb 2, 2012 · The recombinant plasmid pET22b-EGFL7 was transformed into E. coli expression strain BL21 (DE3) cells. One colony was picked up and was grown in 3 ml LB … red oak lounge menuWebJan 7, 2024 · EGFL7, with a relative molecular weight of 29 kDa and 278 amino acids, can be deposited in the extracellular matrix (ECM) with a head-to-tail linkage. red oak lodge waltham forestWebEGFL7 expression promoted glioma growth in experimental glioma models in vivo and stimulated tumor vascularization. Mechanistically, this was mediated by an upregulation … rich buturlaWebFeb 26, 2024 · EGFL7 was upregulated in CRC cell lines. a The mRNA level of EGFL7 in CRC cell lines (SW480, SW620, HT29, LS174T, LoVo) and normal intestinal epithelial cells (HIEC) were determined by RT-PCR assay. b, c The protein expression of EGFL7 was measured using Western blot analysis with GAPDH as an internal protein loading … rich buyerWebFeb 15, 2014 · Data showed that VE-statin/Egfl7 protein was mainly expressed in the cytoplasm of cancer and vascular endothelial cells and was significantly related to the degree of malignancy (t=4.399, P<0.01). Additionally, VE-statin/Egfl7 expression was low in certain gray-matter neurons but undetectable in glial cells. rich buttery cheese