WebSep 1, 2024 · For the screening of active compounds, 1 μg/ml of cryptanshinone, tanshinone I and tanshinone IIA were used. Phenylthiourea supplemented embryo medium was used to inhibit melanization as described before (Karlsson et al., 2001). o … WebCryptanshinone inhibits the glycolysis and inhibits cell migration through PKM2/β-catenin axis in breast cancer. Jiefeng Zhou, Chih Ming Su, Hsin An Chen, Shicong Du, Chang Wei Li, Haoran Wu, Shin Han Tsai, Yu Ting Yeh. Department of Surgery; Taipei Medical University Shuang Ho Hospital;
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WebSep 26, 2013 · Cryptotanshinone inhibited SHP2 with an IC50 of 22.50 μM. Fluorescence titration experiments confirmed that it directly bound to SHP2. Enzymatic kinetic analyses showed that cryptotanshinone was a mixed-type and irreversible inhibitor. This drug was further verified for its ability to block SHP2-mediated cell signaling and cellular functions. WebThe antitumor mechanisms of tanshinone IIA are as follows: (1) inhibiting the growth and proliferation of cancer cells, (2) inducing apoptosis, (3) inducing cell cycle arrest, and (4) … slow download speed in edge
Cryptanshinone inhibits the glycolysis and inhibits cell migration ...
WebAug 13, 2024 · The purpose of this study was to analyze the activity of cryptanshinone, a traditional Chinese medicine monomer, in combination with fosfomycin against … WebCryptanshinone inhibits the glycolysis and inhibits cell migration through PKM2/β-catenin axis in breast cancer. / Zhou, Jiefeng; Su, Chih Ming; Chen, Hsin An et al. In: OncoTargets and Therapy, Vol. 13, 2024, p. 8629-8639. Research output: Contribution to journal › … WebFeb 24, 2024 · In addition, the structures of compounds arucadiol (2), 15,16-dihydrotanshinone I (4), methyl tanshinonate (5), cryptanshinone (7), 1,2-dihydrotanshinquinone I (9), and tanshinone IIA (10) were characterized by mass spectrometry and X-ray crystallographic analysis, and they were confirmed to be active … software development companies germany